Precision Synthesis.
Partnership-Driven.
Custom synthesis of APIs, pharmaceutical intermediates, impurity standards and drug product compounds — from milligram to kilogram scale.
End-to-End Synthesis Solutions
From early-stage research quantities to multi-kilogram production batches, KMCS India delivers complex synthesis with precision and confidentiality.
API Custom Synthesis
mg to kgMulti-step synthesis of active pharmaceutical ingredients to your exact specifications. We handle complex molecular architectures, chiral centres, and sensitive functional groups with rigorous quality control.
Pharmaceutical Intermediates
mg to kgSynthesis of key intermediates for your API manufacturing process. We optimise routes for yield, purity, and scalability — reducing your development timelines and cost of goods.
Impurity Standards & Reference Compounds
mg to gSynthesis and characterisation of known and unknown impurities, degradation products, and reference standards for regulatory submissions and analytical method development.
Drug Product Related Synthesis
mg to kgSynthesis of drug product-related compounds including metabolites, forced degradation products, and labelled compounds to support your formulation and stability studies.
Synthesis at Every Scale
Our capabilities span the full development continuum — from discovery-stage milligram quantities to multi-kilogram process scale-up.
Scale Range
State-of-the-Art Synthesis Infrastructure
Our fully equipped synthesis facility supports reactions from discovery scale to multi-kilogram production.
Glass Jacketed Reactors
50 mL – 50 L
High-Pressure Autoclave Reactors
Up to 200 bar
Rotary Evaporators
2 L – 20 L
Thin Film Evaporators
Industrial scale
Column Chromatography Systems
Preparative scale
Preparative HPLC
Reverse & normal phase
Lyophilisers (Freeze Dryers)
Lab to pilot scale
Vacuum Tray Dryers
Multiple trays
Fractional Distillation Units
Atmospheric & vacuum
Cryogenic Reaction Systems
Down to −78°C
Parr Hydrogenation Apparatus
High-pressure H₂
Overhead Stirrers & Mechanical Mixers
Various capacities
Comprehensive Analytical Capabilities
Full in-house analytical support ensures every compound meets your purity, identity, and regulatory requirements.
High-Performance Liquid Chromatography
Purity, assay, related substances
Liquid Chromatography–Mass Spectrometry
Molecular weight confirmation, impurity identification
Gas Chromatography
Residual solvents, volatile impurities
Gas Chromatography–Mass Spectrometry
Volatile compound identification
Nuclear Magnetic Resonance Spectroscopy
Structure elucidation (¹H, ¹³C)
Infrared Spectroscopy (FTIR)
Functional group identification
UV-Visible Spectrophotometry
Quantitative analysis, chromophore detection
Karl Fischer Titration
Water content determination
Optical Rotation / Polarimetry
Chiral purity, enantiomeric excess
Differential Scanning Calorimetry
Melting point, polymorphism, purity
Thermogravimetric Analysis
Thermal stability, moisture content
Elemental Analysis (C, H, N, S)
Elemental composition confirmation
The Partner Pharma Companies Trust
We combine deep synthetic expertise with the confidentiality, compliance, and responsiveness that pharmaceutical development demands.
Deep Synthetic Expertise
Our team of experienced synthetic chemists brings decades of combined expertise in complex molecule synthesis, route scouting, and process optimisation across diverse therapeutic areas.
Strict Confidentiality
Every project is protected by comprehensive NDAs. Your intellectual property, molecular structures, and project details remain strictly confidential throughout and beyond our engagement.
Regulatory Compliance
All synthesis and analytical work follows ICH guidelines. We provide complete documentation — CoA, NMR spectra, HPLC chromatograms — ready for regulatory submissions.
Ready to Discuss Your Synthesis Challenge?
Whether you need milligram quantities for early discovery or kilogram batches for clinical supply, we have the expertise and infrastructure to deliver.